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Radiology News


Blood brain barrier in Radiology

  • Why do brain pathologies enhance on Gd MRI: Contrast will not leak into the brain until the Blood brain  barrier is damaged.  Enhancement is seen when a CNS tumor destroys the BBB.  
  • Extra-axial tumors such as meningiomas and schwannomas are not derived from brain cells and do not have a blood-brain barrier. Therefore they will enhance.
  • In gliomas - like astrocytomas, oligodendrogliomas and glioblastoma multiforme - enhancement usually indicates a higher degree of malignancy.
  • Gangliogliomas and pilocytic astrocytomas are the exceptions to this rule: they are low-grade tumors, but they enhance vividly. 
Blood brain barrier in Radiology Reviewed by Sumer Sethi on Monday, May 12, 2014 Rating: 5

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