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Multisystem Atrophy versus Parkinsonism-MRI- Teaching Points


What your Neurologist wants to know?

 Brain MRI in patients with MSA-P and MSA-C may reveal atrophy of the putamen, pons, and middle cerebellar peduncles. On T2 MRI sequences, signal changes include hypointensity of the posterior putamen (also described as a slit-like void), a hyperintense lateral putaminal rim, and hyperintensities of the middle cerebellar peduncles. These changes are supportive of the diagnosis of MSA rather than idiopathic Parkinson disease.  The "hot cross bun sign" refers to hyperintense T2 signal in the shape of a cross within the pons that arises from degeneration of transverse pontocerebellar fibers.

Multisystem Atrophy versus Parkinsonism-MRI- Teaching Points Reviewed by Sumer Sethi on Thursday, April 04, 2013 Rating: 5

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