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Radiology News


Methanol Poisoning : MRI

Clinical Features
 21 year old : accidentally had methanol ingestion, developed visual complete visual loss and high anion gap metabolic acidosis. 

Mechanism of Action 
 Methanol ----- metabolized into formaldehyde----- formate------  highly toxic respiratory chain metabolism toxin----  inhibits cytochrome oxidase

MRI findings 
Methanol poisoning characteristically tends to bilaterally affect the putamen, optic nerves, and retina, but can also affect other basal ganglia nuclei, subcortical white matter, and cerebellum. In this patient because MRI was done in acute setting revealed hyperintense signal on DW-MRI for diffusion restriction.

Methanol Poisoning : MRI Reviewed by Sumer Sethi on Monday, April 20, 2020 Rating: 5

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