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Grey matter heterotopia-MRI

 Grey matter heterotopias are believed to be due interruption of the normal migration of neurons from the periventricular telencephalic germinal matrix to the cortex and may be due to either genetic abnormalities or infection / trauma. Neuroblasts proliferate in the germinal matrix between  7 and 8 weeks of gestation. Migration take place from 8 to 26 weeks gestation, and is maximal between 8 and 16 weeks. This is best evaluated by MRI but CT may show with heterotopic grey matter having slightly higher density than the surrounding white matter and can thus be seen if sufficiently large. This is a case of young child with refractory epilepsy with CT shows areas of heterotopic gray matter. MRI was suggested.

Grey matter heterotopia-MRI Reviewed by Sumer Sethi on Friday, February 03, 2012 Rating: 5

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