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A T-2 weighted MR image-Axial section brain

An unique opportunity to win my book "Review Of Radiology".All you have to do is diagnose this case post your answers as comments here and send your full name,current occupation and postal address to sumerdoc-AT-yahoo-DOT-com.

NOTE-In case of many correct entries the prize would be given by a lucky draw.


Schizencephaly is one of the migrational disorders of brain, which include lissencephaly, pachygyria, heterotopia, and is characterized by a gray matter lined cleft that extends from the ependymal surface of the brain through the white matter to the pia.
Two types are recognized: type I, or closed lip schizencephaly, in which the cleft walls are in apposition, and type II, or open lip schizencephaly, in which the walls are separated. In either instance the cleft is lined by heterotopic gray matter. The clefts can be unilateral or bilateral, symmetric or asymmetric.
Bilateral clefts have a worse prognosis for development, with seizures present in the majority. Patients may present with hemiparesis (more likely in unilateral forms) or tetraparesis (more likely in bilateral forms). Mental retardation and seizures are other common presentations, being more severe in bilateral clefts.
CT scans of closed lip schizencephaly may show only a slight outpouching, or "nipple" at the ependymal surface of the cleft. The full thickness cleft or the pial-ependymal seam may be difficult to detect on CT scans. Open lip schizencephaly has a larger, more apparent gray matter lined CSF cleft. The majority of patients have bilateral clefts, most of them roughly symmetrical in location and more likely open (type II) than closed (type I) the presence of heterotopic gray matter is considered pathognomic for schizencephaly, distinguishing it from an acquired condition.
Schizencephaly was earlier considered a rare anomaly but now with advent of axial imaging (CT and MRI) this condition is more frequently recognized.

IMAGE QUIZ Reviewed by Sumer Sethi on Wednesday, March 16, 2005 Rating: 5


Anonymous said...

Closed lip schizencephaly with gray matter heterotopy.

JB said...

Great blog.

Is there a blog listing for medblogs?



Sumer Sethi said...

well thanks for the response, correct answer after a week!! and im not aware blog listing for medblogs..

Anonymous said...

well...whats the answer?

Anonymous said...

well...whats the answer?

Sumer Sethi said...

Well the correct answer has been put up!! and Sergio Z got it absolutely right!! dear Sergio you can claim ur prize by writting a mail to me at sumerdoc-AT-yahoo-dot-com

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